Scientific Publications

OpRegen Program

Posters

PI/IIa Study of Subretinally Transplanted Human Embryonic Stem Cell-Derived RPE Cells (OpRegen) in Advanced Dry-Form AMD Patients, Women in Ophthalmology Summer Symposium 2019, August 22-25, 2019.


Papers

Pluripotent Stem Cells for Retinal Tissue Engineering: Current Status and Future Prospects. Singh R, Cuzzani O, Binette F, Sternberg H, West MD, Nasonkin IO. Stem Cell Rev. 2018 Aug;14(4):463-483.

Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation. McGill TJ, Bohana-Kashtan O, Stoddard JW, Andrews MD, Pandit N, Rosenberg-Belmaker LR, Wiser O, Matzrafi L, Banin E, Reubinoff B, Netzer N, Irving C. Transl Vis Sci Technol. 2017 Jun 14;6(3):17

Characterization of Three-Dimensional Retinal Tissue Derived from Human Embryonic Stem Cells in Adherent Monolayer Cultures. Singh RK, Mallela RK, Cornuet PK, Reifler AN, Chervenak AP, West MD, Wong KY, Nasonkin IO. Stem Cells Dev. 2015 Dec 1;24(23):2778-95.

Directed Differentiation of Human Embryonic Stem Cells into Functional Retinal Pigment Epithelium Cells, Idelson M., et al, Cell Stem Cell. 2009 Oct 2;5(4):396-408.

OPC1 Program

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cells: Preclinical Efficacy and Safety in Cervical Spinal Cord Injury. Manley NC, Priest CA, Denham J, Wirth ED 3rd, Lebkowski JS. Stem Cells Transl Med. 2017 Oct;6(10):1917-1929

Preclinical safety of human embryonic stem cell-derived oligodendrocyte progenitors supporting clinical trials in spinal cord injury. Priest CA, Manley NC, Denham J, Wirth ED 3rd, Lebkowski JS. Regen Med. 2015 Nov;10(8):939-58.

Other Publications

Derivation of Xeno-Free and GMP-Grade Human Embryonic Stem Cells – Platforms for Future Clinical Applications, Tannenbaum SE, Tako Turetsky T, Singer O, Aizenman E, Kirshberg S, et al. (2012). PLOS ONE 7(6): e35325